BDBM288165 (1R,2R)-N7'-(3-chloro-2- fluorobenzyl)-2'-cyclopropyl- 9'-hydroxy-N2,N2-dimethyl- 1',8'-dioxo-1',2',3',8'- tetrahydrospiro[cyclopropane- 1,4'-pyrido[1,2-a]pyrazine]- 2,7'-dicarboxamide::US10087178, Example T33

SMILES CN(C)C(=O)[C@@H]1C[C@]11CN(C2CC2)C(=O)c2c(O)c(=O)c(cn12)C(=O)NCc1cccc(Cl)c1F

InChI Key InChIKey=TURLGOSRTIHYDC-OWJWWREXSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288165   

TargetProtein Nef(Human immunodeficiency virus type 1 (isolate BRU/L...)
Japan Tobacco

US Patent
LigandPNGBDBM288165((1R,2R)-N7'-(3-chloro-2- fluorobenzyl)-2'-cyclopro...)
Affinity DataEC50:  3.30nMT: 2°CAssay Description:The medium (40 μL), a test substance (10 μL) diluted with the medium, and a 1×105 cells/mL MT-4 cell suspension (50 μL) wherein HIV-1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent