BDBM288209 7-Chloro-5-(2-ethyl-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-::US10087185, Example 27

SMILES CCc1nc2ccc(c(-c3cc4CC(=O)Nc4c(Cl)c3)n2n1)C(F)(F)F

InChI Key InChIKey=RMHXQZMYTXEUKP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288209   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288209(7-Chloro-5-(2-ethyl-6-(trifluoromethyl)-[1,2,4]tri...)
Affinity DataIC50:  1.26nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent