BDBM288212 8-Chloro-2-ethyl-5-(7-methyl-1H-indazol-5-yl)-6-(trifluoromethyl)-::US10087185, Example 30

SMILES CCc1nc2c(Cl)cc(c(-c3cc(C)c4[nH]ncc4c3)n2n1)C(F)(F)F

InChI Key InChIKey=GSZYMMZSGGJQAY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288212   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288212(8-Chloro-2-ethyl-5-(7-methyl-1H-indazol-5-yl)-6-(t...)
Affinity DataIC50:  3.98nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent