BDBM288229 5-(6-(Difluoromethyl)-2-ethyl-[1,2,4]triazolo[1,5-a]pyridin-5-yl)-7-::US10087185, Example 47

SMILES CCc1nc2ccc(C(F)F)c(-c3cc4CC(=O)Nc4c(C)c3)n2n1

InChI Key InChIKey=IQCDBVKHJFLEGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288229   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288229(5-(6-(Difluoromethyl)-2-ethyl-[1,2,4]triazolo[1,5-...)
Affinity DataIC50:  3.98nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent