BDBM288527 (1R,3R,5S,6r)-3-[8- amino-1-(2-ethoxy-4- {[4- (trifluoromethyl) pyridin-2- yl]carbamoyl}phenyl) imidazo[1,5-a]pyrazin- 3- yl]bicyclo[3.1.0] hexane-6-carboxylic acid::US10087188, Example 135
SMILES CCOc1cc(ccc1-c1nc([C@H]2C[C@H]3[C@@H](C2)[C@@H]3C(O)=O)n2ccnc(N)c12)C(=O)Nc1cc(ccn1)C(F)(F)F
InChI Key InChIKey=FEOJBYAAHMWGTQ-DNEIQLIYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288527
Affinity DataIC50: 0.430nMAssay Description:BTK enzymatic activity was determined with the LANCE (Lanthanide Chelate Excite) TR-FRET (Time-resolved fluorescence resonance energy transfer) assay...More data for this Ligand-Target Pair