BDBM289087 N-[(1S)-2-[4-[2-[4-Amino- 6-methyl-2- (trifluoromethyl)pyrimidin- 5-yl]ethyl]-1-piperidyl]- 1-methyl-2-oxo-ethyl]-3- chloro-pyrazine-2- carboxamide::US10093651, Example 15

SMILES C[C@H](NC(=O)c1nccnc1Cl)C(=O)N1CCC(CCc2c(C)nc(nc2N)C(F)(F)F)CC1

InChI Key InChIKey=PVYCMWDQZYMIBD-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289087   

TargetGhrelin O-acyltransferase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM289087(N-[(1S)-2-[4-[2-[4-Amino- 6-methyl-2- (trifluorome...)
Affinity DataIC50:  55.7nMpH: 7.5Assay Description:Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO to obtain a ten-point dilution curve wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent