BDBM289090 Methyl-[(1S)-2-[4-[2-[4-amino-6-methyl-2-(trifluoromethyl)pyrimidin-5-yl]ethyl]-1-piperidyl]-1-methyl-2-oxo-ethyl]carbamate::US10093651, Example 20

SMILES COC(=O)N[C@@H](C)C(=O)N1CCC(CCc2c(C)nc(nc2N)C(F)(F)F)CC1

InChI Key InChIKey=DKDJHOHQFAHDLU-NSHDSACASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289090   

TargetGhrelin O-acyltransferase(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM289090(Methyl-[(1S)-2-[4-[2-[4-amino-6-methyl-2-(trifluor...)
Affinity DataIC50:  615nMpH: 7.5Assay Description:Prepare test compounds in DMSO to make up a 0.2 mM stock solution. Serially dilute the stock solution in DMSO to obtain a ten-point dilution curve wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent