BDBM289166 US10093660, Example 1.36::US10093660, Example 2.67

SMILES Cc1cc(cc2ncnc(Nc3ccc(F)cc3O[C@@H]3COC[C@@H]3O)c12)N=S1(=O)CCC1

InChI Key InChIKey=TZHJOOVYOQMSSP-AZUAARDMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 289166   

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec Internatonal

US Patent
LigandPNGBDBM289166(US10093660, Example 1.36 | US10093660, Example 2.6...)
Affinity DataIC50:  4nMT: 2°CAssay Description:ASSAY SETUP: The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Evotec Internatonal

US Patent
LigandPNGBDBM289166(US10093660, Example 1.36 | US10093660, Example 2.6...)
Affinity DataIC50:  3nMT: 2°CAssay Description:ASSAY SETUP: The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent