BDBM28923 (2S)-N-(4-chlorophenyl)-3-ethyl-1-hydroxypentane-2-sulfonamido::BMCL184232 Compound 8e::Begacestat analogue, 7
SMILES CCC(CC)[C@@H](CO)NS(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=KBVZDYCSYMTCEV-CYBMUJFWSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 28923
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataEC50: 294nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataEC50: 294nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair