BDBM289509 5-(2-isopropyl-1-(3-(4- methylpiperazin-1-yl)- bicyclo[1.1.1]pentan-1- yl)-1H-imidazol-4-yl)- 3-(trifluoromethoxy)- pyridin-2-amine::US10093664, Example 74

SMILES CC(C)c1nc(cn1C12CC(C1)(C2)N1CCN(C)CC1)-c1cnc(N)c(OC(F)(F)F)c1

InChI Key InChIKey=BTLRWVSEIUQULA-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289509   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
The University of Texas System

US Patent
LigandPNGBDBM289509(5-(2-isopropyl-1-(3-(4- methylpiperazin-1-yl)- bic...)
Affinity DataKd:  4.5nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent