BDBM290370 (3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-carboxylic acid::US10098902, Example 6::US10603330, Example 6::US11389464, Example 6

SMILES N[C@]1(CCNC[C@H]1CCCB(O)O)C(O)=O

InChI Key InChIKey=QGCXHYHXXBYKHC-APPZFPTMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 290370   

TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  625nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  3.50E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  3.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  625nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetArginase-1(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM290370((3R,4S)-4-amino-3-(3-boronopropyl)piperidine-4-car...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent