BDBM292581 (S)-2-(((1H-imidazol-2-yl)methyl)amino)-N-(2-(diethylamino)propyl)-6-(5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl)isonicotinamide::US10100058, Example 237

SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(NCc2ncc[nH]2)nc(c1)-c1cnn2ccc(nc12)-c1cccs1

InChI Key

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292581   

TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292581((S)-2-(((1H-imidazol-2-yl)methyl)amino)-N-(2-(diet...)
Affinity DataEC50:  148nMAssay Description:CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM292581((S)-2-(((1H-imidazol-2-yl)methyl)amino)-N-(2-(diet...)
Affinity DataIC50:  0.130nMAssay Description:The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent