BDBM29265 quinolinone, 35

SMILES Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

InChI Key InChIKey=HBCGDPSRYUIERE-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29265   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29265(quinolinone, 35)
Affinity DataEC50:  170nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29265(quinolinone, 35)
Affinity DataEC50: >1.00E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys

LigandPNGBDBM29265(quinolinone, 35)
Affinity DataEC50: >1.00E+5nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed