BDBM293676 3-({[(4R)-7-[methyl(phenyl)amino]-3,4-dihydro-2H-1-benzopyran-::US10106534, Example 18

SMILES CN(c1ccccc1)c1ccc2[C@H](CNc3cnccc3C(O)=O)CCOc2c1

InChI Key InChIKey=NGFBRSRFMOGCMY-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293676   

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293676(3-({[(4R)-7-[methyl(phenyl)amino]-3,4-dihydro-2H-1...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293676(3-({[(4R)-7-[methyl(phenyl)amino]-3,4-dihydro-2H-1...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent