BDBM293712 3-({[(4S)-7-[(4-fluorophenyl)sulfanyl]-3,4-dihydro-2H-1-::US10106534, Example 54

SMILES OC(=O)c1ccncc1NC[C@H]1CCOc2cc(Sc3ccc(F)cc3)ccc12

InChI Key InChIKey=KFERCOIZQGSFCJ-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293712   

TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293712(3-({[(4S)-7-[(4-fluorophenyl)sulfanyl]-3,4-dihydro...)
Affinity DataIC50:  550nMT: 2°CAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM293712(3-({[(4S)-7-[(4-fluorophenyl)sulfanyl]-3,4-dihydro...)
Affinity DataIC50:  5.50E+3nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent