BDBM294483 1-(1-(Cyclopropylmethyl)-2-(2-(5, 8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)ethyl)-1H-imidazol-4-yl)pyridin-2(1H)-one::US9586970, 4
SMILES Cc1cnc(C)c2nc(CCc3nc(cn3CC3CC3)-n3ccccc3=O)nn12
InChI Key InChIKey=SINWXYZUDOWMAJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294483
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 150nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair