BDBM294489 1-{2-[(E)-2-{4,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}ethenyl]-1-methyl-1H-imidazol-4-yl}pyrrolidin-2-one::US9586970, 10
SMILES Cc1cnc(C)c2nc(\C=C\c3nc(cn3C)N3CCCC3=O)nn12
InChI Key InChIKey=KLLQOHYGEXPJOP-VOTSOKGWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294489
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 54.6nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair