BDBM294492 1-[2-(2-{4,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}ethyl)-1-(2,2,2-trifluoroethyl)-1H-imidazol-4-yl]pyrrolidin-2-one::US9586970, 13
SMILES Cc1cnc(C)c2nc(CCc3nc(cn3CC(F)(F)F)N3CCCC3=O)nn12
InChI Key InChIKey=BFRBIYWZJHQSLU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294492
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 36.7nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair