BDBM294495 1-[1-(Cyclopropylmethyl)-2-(2-{5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl}ethyl)-1H-imidazol-4-yl]pyrrolidin-2-one::US9586970, 16
SMILES Cc1cnc(C)n2nc(CCc3nc(cn3CC3CC3)N3CCCC3=O)nc12
InChI Key InChIKey=HOKBYPVVCODXTK-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294495
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 14.8nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair