BDBM294499 1-{2-[(E)-2-{4,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl}ethenyl]-1-phenyl-1H-imidazol-4-yl}pyrrolidin-2-one::US9586970, 20
SMILES Cc1cnc(C)n2nc(\C=C\c3nc(cn3-c3ccccc3)N3CCCC3=O)nc12
InChI Key InChIKey=OCICYHNNUDBBEY-ZHACJKMWSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294499
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 19.4nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair