BDBM294504 1-(2-{2-[3-methyl-2-(trifluoromethyl) imidazo[1, 2-b]pyridazin-6-yl]ethynyl}-1-phenyl-1H-imidazol-4-yl) pyrrolidin-2-one::US9586970, 25

SMILES Cc1c(nc2ccc(nn12)C#Cc1nc(cn1-c1ccccc1)N1CCCC1=O)C(F)(F)F

InChI Key InChIKey=MVUJSSOMFNUNES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 294504   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM294504(1-(2-{2-[3-methyl-2-(trifluoromethyl) imidazo[1, 2...)
Affinity DataIC50:  21.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent