BDBM294504 1-(2-{2-[3-methyl-2-(trifluoromethyl) imidazo[1, 2-b]pyridazin-6-yl]ethynyl}-1-phenyl-1H-imidazol-4-yl) pyrrolidin-2-one::US9586970, 25
SMILES Cc1c(nc2ccc(nn12)C#Cc1nc(cn1-c1ccccc1)N1CCCC1=O)C(F)(F)F
InChI Key InChIKey=MVUJSSOMFNUNES-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 294504
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 21.9nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM...More data for this Ligand-Target Pair