BDBM29455 Pyrazolo[1,5-a]-1,3,5-triazine, 12-24

SMILES COc1cc(C)c(-c2c(C)nn3c(nc(C)nc23)N(C)CC=C)c(OC)c1

InChI Key InChIKey=QUKQYNSOWIXXCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29455   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb

LigandPNGBDBM29455(Pyrazolo[1,5-a]-1,3,5-triazine, 12-24)
Affinity DataIC50:  4.92nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed