BDBM29528 ML10302 scaffold, 9{a;y}

SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CC1)NC(=O)CCCCCN1C(=O)c2cccc3c(N)ccc(C1=O)c23

InChI Key InChIKey=BVSHRWXIROPTPP-UHFFFAOYSA-N

Data  1 KI  1 EC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29528   

Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Cnrs

LigandPNGBDBM29528(ML10302 scaffold, 9{a;y})
Affinity DataKi:  111nM ΔG°:  -9.48kcal/mole EC50:  4nMpH: 7.4 T: 2°CAssay Description:Radioligand binding studies were performed in buffer contains test compound, [3H]-GR113808, and receptor C6 glial cell membrane preparation. Nonspeci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Cnrs

LigandPNGBDBM29528(ML10302 scaffold, 9{a;y})
Affinity DataAssay Description:EC/IC50 was the effective concentration of agonist inhibiting the formation of A-beta fibrils to 50% of the control value. Three independent measurem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed