BDBM29546 benzimidazolone scaffold, 15d

SMILES COc1ccccc1N1CCN(CCCn2c3ccccc3[nH]c2=O)CC1

InChI Key InChIKey=YERGVXFJQYPXLJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29546   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM29546(benzimidazolone scaffold, 15d)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Cnrs

LigandPNGBDBM29546(benzimidazolone scaffold, 15d)
Affinity DataKi:  3.40nM ΔG°:  -12.0kcal/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM29546(benzimidazolone scaffold, 15d)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM29546(benzimidazolone scaffold, 15d)
Affinity DataKi:  40nMAssay Description:Competition experiments were performed in the presence radioligand with membrane protein and test compounds. After incubation, the reaction stopped b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed