BDBM29612 CHEMBL33103::CVD-0001578::JOH-MSK-a63bdd1d-4::N-ACETYL SEROTONIN::N-Acetyl-5-hydroxytryptamine::N-Acetyltryptamine,5-Hydroxy::N-acetylserotonin::Normelatonin::Serotonin,N-acetyl

SMILES CC(=O)NCCc1c[nH]c2ccc(O)cc12

InChI Key InChIKey=MVAWJSIDNICKHF-UHFFFAOYSA-N

Data  14 KI  7 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 29612   

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  79.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  148nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  189nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  210nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  223nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor(RABBIT)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  273nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  302nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  339nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  347nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  398nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  850nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1C(Gallus gallus)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  1.64E+3nMAssay Description:In vitro binding affinity against melatonin receptor using 2-[125I]iodomelatonin (0.05 nM) and chicken brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor(RABBIT)
Northwestern University

Curated by PDSP Ki Database
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  3.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
National Institute Of Advanced Industrial Science And Technology

Curated by ChEMBL
LigandPNGBDBM29612(CHEMBL33103 | CVD-0001578 | JOH-MSK-a63bdd1d-4 | N...)
Affinity DataKi:  2.40E+5nMAssay Description:Apparent noncompetitive inhibition of catecholase activity of tyrosinase in mouse B16 cells by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed