BDBM29746 N-methyl-alanine tripeptide inhibitor, 2b

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)N(C)C(=O)CCC(C)C

InChI Key InChIKey=NKFWCEAWYLPBHG-ANULTFPQSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 29746   

TargetCathepsin D(Homo sapiens (Human))
Novartis

LigandPNGBDBM29746(N-methyl-alanine tripeptide inhibitor, 2b)
Affinity DatapH: 3.1 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1 [1-453](Homo sapiens (Human))
Novartis

LigandPNGBDBM29746(N-methyl-alanine tripeptide inhibitor, 2b)
Affinity DataIC50:  2.40E+3nMpH: 4.5 T: 2°CAssay Description:Inhibition assays were done in black 96-well plates by adding test compounds to the respective enzyme in assay buffer. Plates were incubated at room ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed