BDBM297737 (R)No FitN-(2-hydroxy-3-(isoindolin-2-yl)propyl)-2-(quinolin-8-yloxy)acetamide::US10118918, Compound 16::US9732072, Compound 16

SMILES O[C@H](CNC(=O)COc1cccc2cccnc12)CN1Cc2ccccc2C1

InChI Key InChIKey=DOONEOBBMQKESC-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297737   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM297737((R)No FitN-(2-hydroxy-3-(isoindolin-2-yl)propyl)-2...)
Affinity DataIC50:  5.50E+3nMAssay Description:General Materials.S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), bicine, KCl, Tween20, dimethylsulfoxide (DMSO), bovine skin gelatin (BSG)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM297737((R)No FitN-(2-hydroxy-3-(isoindolin-2-yl)propyl)-2...)
Affinity DataIC50:  5.50E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% BSG, and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent