BDBM298350 US10124009, Compound 5

SMILES Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)OCCCCCCO)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=UNDUDUVCURNARG-FQEVSTJZSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 298350   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Tensha Therapeutics

US Patent
LigandPNGBDBM298350(US10124009, Compound 5)
Affinity DataKd:  430nMAssay Description:A BROMOscan binding assay was utilized to test the in vitro binding activity of (S)-Compounds 1, 2, 3, 4, 5 and 7 to the first and second bromodomain...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Tensha Therapeutics

US Patent
LigandPNGBDBM298350(US10124009, Compound 5)
Affinity DataKd:  0.430nMAssay Description:Inhibition of biotin-labeled acetylated peptide binding to BRD4 bromodomain 1 (unknown origin) expressed in Escherichia coli BL21 after 1 hr by BROMO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIsoform C of Bromodomain-containing protein 4 (Short)(Homo sapiens (Human))
Tensha Therapeutics

US Patent
LigandPNGBDBM298350(US10124009, Compound 5)
Affinity DataKd:  400nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent