BDBM298372 (S)-1-((S)-1-(4-(benzyloxy)-3-(trifluoromethyl)benzoyl)-4,4-difluoropyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 20::US10611727, Example 20

SMILES FC(F)(F)c1cc(ccc1OCc1ccccc1)C(=O)N1CC(F)(F)C[C@H]1C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=KYOISHPHSGUAGP-ICSRJNTNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298372   

TargetProlyl endopeptidase-like(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298372((S)-1-((S)-1-(4-(benzyloxy)-3-(trifluoromethyl)ben...)
Affinity DataIC50:  4.5nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase(Homo sapiens (Human))
Universitat De Barcelona

US Patent
LigandPNGBDBM298372((S)-1-((S)-1-(4-(benzyloxy)-3-(trifluoromethyl)ben...)
Affinity DataIC50:  4.5nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent