BDBM29886 alkynyl ether, 28
SMILES OC(=O)COc1ccc(Sc2ccc(COc3ccc(cc3)C(F)(F)F)cc2OCC#Cc2cccnc2)c2CCCCc12
InChI Key InChIKey=NUJKYSJRDHOZSO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 29886
Affinity DataKi: 16nM EC50: 680nMAssay Description:The human PPARdelta ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Affinity DataKi: 25nM EC50: 1.60E+3nMAssay Description:The human PPARgamma ligand binding was directly measured using a filtration assay in a UniFilter 350 96-well assay plate (Polyfiltronics). The reacti...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nM ΔG°: -8.10kcal/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair