BDBM299423 N-[3-(4-amino- quinazolin-6-yl) phenyl]-2- pyrrolidin-1-yl- acetamide::US9592235, Example 216::US9855269, Compound 63

SMILES Nc1ncnc2ccc(cc12)-c1cccc(NC(=O)CN2CCCC2)c1

InChI Key InChIKey=RQVUVEKKIZVJGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299423   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299423(N-[3-(4-amino- quinazolin-6-yl) phenyl]-2- pyrroli...)
Affinity DataIC50:  216nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299423(N-[3-(4-amino- quinazolin-6-yl) phenyl]-2- pyrroli...)
Affinity DataIC50:  216nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent