BDBM299436 N6-[2-(4-fluoro- phenyl)ethyl] pyrido[3,2-d] pyrimidine- 4,6-diamine::US9592235, Example 225::US9855269, Compound 72
SMILES Nc1ncnc2ccc(NCCc3ccc(F)cc3)nc12
InChI Key InChIKey=MAUQWFRCYUDOSP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 299436
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 70.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 70.1nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair