BDBM299462 6-(amino-5-fluoro- phenyl)pyrido [3,2-d]pyrimidin- 4-amine::US9592235, Example 243::US9855269, Compound 90

SMILES Nc1cc(F)cc(c1)-c1ccc2ncnc(N)c2n1

InChI Key InChIKey=YUUUJXGJNRIIOJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299462   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299462(6-(amino-5-fluoro- phenyl)pyrido [3,2-d]pyrimidin-...)
Affinity DataIC50:  16.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299462(6-(amino-5-fluoro- phenyl)pyrido [3,2-d]pyrimidin-...)
Affinity DataIC50:  16.9nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent