BDBM299485 6-[3-(6-methyl-2- pyridyl)-1- piperidyl]pyrido [3,2-d]pyrimidin- 4-amine::US9592235, Example 258::US9855269, Compound 105

SMILES Cc1cccc(n1)C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=VNBYTQFVKREWQL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299485   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299485(6-[3-(6-methyl-2- pyridyl)-1- piperidyl]pyrido [3,...)
Affinity DataIC50:  145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299485(6-[3-(6-methyl-2- pyridyl)-1- piperidyl]pyrido [3,...)
Affinity DataIC50:  145nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent