BDBM299490 N-[3-(4-amino- pyrido[3,2-d] pyrimidin-6-yl)- 5-fluoro-phenyl]- 2-cyclopentyl- acetamide::US9592235, Example 263::US9855269, Compound 110
SMILES Nc1ncnc2ccc(nc12)-c1cc(F)cc(NC(=O)CC2CCCC2)c1
InChI Key InChIKey=NWOSZYGCZLWAOJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 299490
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 107nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 107nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair