BDBM299492 2-(4-amino- quinazolin- 6-yl)phenyl::US9592235, Example 265::US9855269, Compound 112
SMILES Nc1ncnc2ccc(cc12)-c1cccc(O)c1
InChI Key InChIKey=LCGQENKQMLKYOP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 299492
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 14.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 14.7nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair