BDBM299545 N-[6-(3-amino-5- fluoro-phenyl) pyrido[3,2-d] pyrimidin-4-yl]- 2-pyrrolidin-1-yl- acetamide::US9592235, Example 315::US9855269, Compound 164

SMILES Nc1cc(F)cc(c1)-c1ccc2ncnc(NC(=O)CN3CCCC3)c2n1

InChI Key InChIKey=CSTPNCAOUKUPQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299545   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299545(N-[6-(3-amino-5- fluoro-phenyl) pyrido[3,2-d] pyri...)
Affinity DataIC50:  232nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299545(N-[6-(3-amino-5- fluoro-phenyl) pyrido[3,2-d] pyri...)
Affinity DataIC50:  232nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent