BDBM299563 N6-[(2-fluoro- phenyl)methyl] pyrido[3,2-d] pyrimidine-4,6- diamine::US9592235, Example 333::US9855269, Compound 230

SMILES Nc1ncnc2ccc(NCc3ccccc3F)nc12

InChI Key InChIKey=JZHMLIUPLWWJJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299563   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299563(N6-[(2-fluoro- phenyl)methyl] pyrido[3,2-d] pyrimi...)
Affinity DataIC50:  253nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM299563(N6-[(2-fluoro- phenyl)methyl] pyrido[3,2-d] pyrimi...)
Affinity DataIC50:  253nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent