BDBM300230 3-[2-(3-chlorophenyl)ethynyl]- N-ethyl-N-isopropyl-3a,4,5,6a- tetrahydropyrrolo[3,2- d]isoxazole-6-carboxamide::US9593127, Example 4

SMILES CCN(C(C)C)C(=O)N1CCC2C1ON=C2C#Cc1cccc(Cl)c1

InChI Key InChIKey=WFBZGOFMGXXXDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300230   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Ireland

US Patent
LigandPNGBDBM300230(3-[2-(3-chlorophenyl)ethynyl]- N-ethyl-N-isopropyl...)
Affinity DataIC50:  6.99nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent