BDBM300237 US9593127, Example 11::[3-[2-(m-tolyl)ethynyl]- 3a,4,5,6a- tetrahydropyrrolo[3,2- d]isoxazol-6-yl]-pyrrolidin-1-yl- methanone

SMILES Cc1cccc(c1)C#CC1=NOC2C1CCN2C(=O)N1CCCC1

InChI Key InChIKey=WTBDDOYXAWYSGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 300237   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Recordati Ireland

US Patent
LigandPNGBDBM300237(US9593127, Example 11 | [3-[2-(m-tolyl)ethynyl]- 3...)
Affinity DataIC50:  17nMAssay Description:Affinity at transmembrane glutamate metabotropic mGluR5 receptor subtypes was evaluated according to the methods of Anderson (Anderson et al., J Phar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent