BDBM300449 N-{4-tert-butyl-3-[(morpholin-4-ylacetyl)amino]phenyl}-5-phenylthiophene-2-carboxamide::US10130633, Example 19

SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(s2)-c2ccccc2)cc1NC(=O)CN1CCOCC1

InChI Key InChIKey=BCIZWNGRDUPVKI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300449   

TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300449(N-{4-tert-butyl-3-[(morpholin-4-ylacetyl)amino]phe...)
Affinity DataIC50:  26.2nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300449(N-{4-tert-butyl-3-[(morpholin-4-ylacetyl)amino]phe...)
Affinity DataIC50: >5.00E+4nMAssay Description:HEK293 cells were cotransfected with the FOP control vector and pcDNA3. The FOP vector is identical to the TOP construct, but it contains instead of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300449(N-{4-tert-butyl-3-[(morpholin-4-ylacetyl)amino]phe...)
Affinity DataIC50:  990nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300449(N-{4-tert-butyl-3-[(morpholin-4-ylacetyl)amino]phe...)
Affinity DataIC50:  1.10E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent