BDBM30131 tetrahydrofuranyl ethylamine, 14

SMILES COc1ccc(F)cc1CCC1CCC(CCN)O1

InChI Key InChIKey=FOEJRTWJHDIANT-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 30131   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30131(tetrahydrofuranyl ethylamine, 14)
Affinity DataKi:  2.10nM ΔG°:  -11.7kcal/mole EC50:  2.5nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30131(tetrahydrofuranyl ethylamine, 14)
Affinity DataKi:  2.44E+3nM EC50:  481nMAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

LigandPNGBDBM30131(tetrahydrofuranyl ethylamine, 14)
Affinity DataKi:  6.50E+3nM ΔG°:  -7.00kcal/mole EC50:  2.79E+4nMpH: 7.4 T: 2°CAssay Description:Binding affinity of each compound was measured by assessing the potency of inhibition of binding of radiolabeled RTI-55. Membranes were preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed