BDBM3016 3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::3-N-(4-aminophenyl)-4-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 17

SMILES Nc1ccc(Nc2[nH]nc3ncnc(Nc4cccc(Cl)c4)c23)cc1

InChI Key InChIKey=KMXFOTQAKQWIOA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3016   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3016(3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)
Affinity DataIC50:  5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3016(3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)
Affinity DataIC50:  1.18E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3016(3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)
Affinity DataIC50: <1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Bos taurus (bovine))
Novartis Pharmaceuticals

LigandPNGBDBM3016(3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)
Affinity DataIC50: >1.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3016(3-((4-Aminophenyl)amino)-4-((3-chlorophenyl)amino)...)
Affinity DataIC50:  2.40E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed