BDBM302387 4-{[4-Amino-5-(5,7-dimethoxy-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-6-yl]methyl}-piperazin-2-one::US9598416, Example 33

SMILES COc1cc(OC)c2sc(cc2c1)-c1c(CN2CCNC(=O)C2)cn2ncnc(N)c12

InChI Key InChIKey=PQBLTKIKXPKVLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302387   

TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM302387(4-{[4-Amino-5-(5,7-dimethoxy-1-benzothiophen-2-yl)...)
Affinity DataIC50:  1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM302387(4-{[4-Amino-5-(5,7-dimethoxy-1-benzothiophen-2-yl)...)
Affinity DataIC50:  2.70nMAssay Description:Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent