BDBM3024 3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 25::N-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES COc1ccc(cc1)-c1[nH]nc2ncnc(Nc3cccc(Cl)c3)c12

InChI Key InChIKey=CNEAVADKWYPXBR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3024   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3024(3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)
Affinity DataIC50:  96nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3024(3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)
Affinity DataIC50:  1.65E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3024(3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Bos taurus (bovine))
Novartis Pharmaceuticals

LigandPNGBDBM3024(3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3024(3-(4-Methoxyphenyl)-4-((3-chlorophenyl)amino)-1H-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed