BDBM3031 3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyrazolo[3,4-d]pyrimidine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 32::4-N-benzyl-3-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine

SMILES Clc1cccc(Nc2[nH]nc3ncnc(NCc4ccccc4)c23)c1

InChI Key InChIKey=LRHDXMDHHMEKIP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 3031   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3031(3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyraz...)
Affinity DataIC50:  870nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3031(3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyraz...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3031(3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyraz...)
Affinity DataIC50:  9.00E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Bos taurus (bovine))
Novartis Pharmaceuticals

LigandPNGBDBM3031(3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyraz...)
Affinity DataIC50:  4.50E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM3031(3-((3-Chlorophenyl)amino)-4-(benzylamino)-1H-pyraz...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed