BDBM30334 3-aryl isoxazole analog, 6c

SMILES CC(C)c1onc(c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1)-c1ccc(cc1Cl)S(C)(=O)=O

InChI Key InChIKey=AAXFUEIVDMVUPT-BQYQJAHWSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 30334   

TargetBile acid receptor(Homo sapiens (Human))
Roche R & D Center(China)

LigandPNGBDBM30334(3-aryl isoxazole analog, 6c)
Affinity DataIC50:  170nM EC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:Binding affinity (IC50) was evaluated using scintillation proximity assay with radiolabeled ligand and biotinylated receptor. Because the scintillant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed