BDBM303380 US10138222, Example 105

SMILES Cc1cc(F)c(cc1-c1cnn(c1)-c1cncc(c1)C1CC1)C(=O)NC1CC1

InChI Key InChIKey=HXBDNPHXKSRSOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303380   

TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303380(US10138222, Example 105)
Affinity DataIC50:  1nMAssay Description:In a 384-well plate, test compound diluted in assay buffer (1% DMSO final) is mixed with 8His-RIPK2 FL enzyme (final concentration of 8 nM). After 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent