BDBM304226 2-(1-((4-carboxy-3- fluorophenyl)amino)-3- cyclopropyl-1-oxopropan-2- yl)-5-(3-chloro-6- (difluoromethyl)-2- fluorophenyl)pyridine 1- oxide::BDBM304227::US10143681, Example 117
SMILES OC(=O)c1ccc(NC(=O)C(CC2CC2)c2ccc(c[n+]2[O-])-c2c(F)c(Cl)ccc2C(F)F)cc1F
InChI Key InChIKey=JJPLFMNEWVLCNA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 304226
Affinity DataIC50: 58.4nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Affinity DataIC50: 14.6nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Kallikrein can be determined using a relevant purified serine protease, a...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair