BDBM304416 (R)-(2-(4-(4-chloro-3-(methylsulfonyl)phenyl)-2-isopropylpiperazin-1-yl)-4-(trifluoromethyl)pyrimidin-5-yl)methanol::US10144715, Compound 11-3

SMILES CC(C)[C@@H]1CN(CCN1c1ncc(CO)c(n1)C(F)(F)F)c1ccc(Cl)c(c1)S(C)(=O)=O

InChI Key InChIKey=PAXOTBRHGNYSDC-INIZCTEOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304416   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304416((R)-(2-(4-(4-chloro-3-(methylsulfonyl)phenyl)-2-is...)
Affinity DataKi:  6nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304416((R)-(2-(4-(4-chloro-3-(methylsulfonyl)phenyl)-2-is...)
Affinity DataKi:  146nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent